Genetic Test Details

Noonan Syndrome and RASopathies

Test Information

Title
Noonan Syndrome and RASopathies
Category
Cardiogenetics, Immunity, Multiple Congenital Anomalies
Sub Category
Noonan Syndrome and RASopathies
Gene/Platform/Region List
BRAF, CBL, HRAS, KRAS, LZTR1, MAP2K1, MAP2K2, NRAS, PTPN11, RAF1, RIT1, SHOC2, SOS1, SOS2, SPRED1 (Dosage ONLY)
Test type
Gene Panel
Samples Accepted
Blood, DNA
Indications
Diagnosis, Prenatal
Test Methodology
CNV, Sequencing
Methodology Notes
NGS; MLPA of SPRED1
Disease/Condition
Noonan syndrome, Noonan-like  syndrome, Costello syndrome, CFC syndrome, LEOPARD syndrome, Legius syndrome

Last Updated: November 26, 2025