TPMT/NUDT15 Panel (Pharmacogenetic testing)
| Test Information | |
|---|---|
| Test Name | TPMT/NUDT15 Panel (Pharmacogenetic testing) |
| Lab (Location) | The Hospital for Sick Children |
| Category | Hematology |
| Subcategory | TPMT/NUDT15 Panel (Pharmacogenetic testing) |
| Gene/Platform/Region List | TPMT (*2, *3A, *3B, *3C), NUDT15 (*3 & *5) |
| Test type | Gene Panel, Targeted Variant |
| Samples Accepted | Blood, DNA, Bone Marrow Aspirate |
| Indications Diagnosis | Pharmacogenetics |
| Test Methodology | Real Time PCR |
| Methodology Notes | Realtime PCR for 3 TPMT Variants (c.238G>C, c.460G>A, c.719A>G) and 2 NUDT15 Variants (c.415C>T & c.52G>A) |
| Diseases/Conditions | New Leukemia Diagnosis |
| Notes | Test Performed in the Clinical Molecular Diagnostics lab |