Hereditary Cancer Panel: BRCA1/BRCA2 Ashkenazi Jewish mutations panel
| Test Information | |
|---|---|
| Test Name | Hereditary Cancer Panel: BRCA1/BRCA2 Ashkenazi Jewish mutations panel |
| Lab (Location) | Children's Hospital of Eastern Ontario |
| Category | Cancer |
| Subcategory | Ashkenazi Jewish Panel |
| Gene/Platform/Region List | BRCA1 (c.5266dupC), BRCA1 (c.68_69delAG), BRCA2 (c.5946delT) |
| Test type | Targeted Variant |
| Samples Accepted | Blood, DNA |
| Indications Diagnosis | Diagnosis, Carrier / Cascade Testing |
| Test Methodology | Sequencing |
| Methodology Notes | Targeted Sanger sequencing for 3 BRCA1/BRCA2 pathogenic founder variants |
| Diseases/Conditions | Hereditary Breast Cancer (Ashkenazi Jewish mutations) |