Hereditary Cancer Panel
| Test Information | |
|---|---|
| Test Name | Hereditary Cancer Panel |
| Lab (Location) | Hamilton Health Sciences Centre |
| Category | Cancer |
| Subcategory | Hereditary Comprehensive Cancer |
| Gene/Platform/Region List | AIP, APC, ATM, AXIN2, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDC73, CDH1, CDK4, CDKN1B, CDKN2A, CHEK2, CTNNA1, DICER1, EGFR, EGLN1, EPCAM, EXT1, EXT2, FH, FLCN, GALNT12, GREM1, HOXB13, KIT, LZTR1, MAX, MEN1, MET, MITF, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NF2, NTHL1, PALB2, PDGFRA, PMS2, POLD1, POLE, POT1, PRKAR1A, PTCH1, PTEN, RAD51C, RAD51D, RB1, RECQL, RET, RNF43, RPS20, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, SMARCB1, SMARCE1, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL |
| Test type | Gene Panel |
| Samples Accepted | Blood |
| Indications Diagnosis | Diagnosis, Carrier / Cascade Testing |
| Test Methodology | Sequencing |
| Methodology Notes | EPCAM and GREM1 CNV only |
| Diseases/Conditions | Hereditary Cancer, Breast Cancer, Lynch Syndrome, Hereditary gastrointestinal (GI), pancreatic adenocarcinoma, colon cancer, germline genetic testing, FM, familial, HCT |