Polyposis
| Test Information | |
|---|---|
| Test Name | Polyposis |
| Lab (Location) | University Health Network |
| Category | Cancer |
| Subcategory | Hereditary Polyposis Syndrome |
| Gene/Platform/Region List | BMPR1A, EPCAM, GALNT12, GREM1, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, NTHL1, PMS2, POLD1, POLE, PTEN, RNF43, RPS20, SMAD4, STK11, TP53, APC |
| Test type | Gene Panel |
| Samples Accepted | Blood, DNA, Saliva |
| Indications Diagnosis | Diagnosis, Carrier / Cascade Testing |
| Test Methodology | CNV, Sequencing |
| Methodology Notes | EPCAM and GREM1 CNV only |
| Diseases/Conditions | Hereditary Colorectal Cancer, Colon Cancer |
| Notes | Saliva samples must be provided in oragene, OG-600 kits; UHN does not provide collection kits but they can be obtained directly from DNA genotek (www.dnagenotek.com) |