9093

GTD Indications Pharmacogenetics GTD Samples Accepted Blood DNA Bone Marrow Aspirate GTD Test Methodology Real Time PCR GTD Methodology Notes Realtime PCR for 3 TPMT Variants (c.238G>C, c.460G>A, c.719A>G) and 2 NUDT15 Variants (c.415C>T & c.52G>A) GTD Notes Test Performed in the Clinical Molecular Diagnostics lab Generic Test name (cms title) TPMT/NUDT15 Panel (Pharmacogenetic testing) GTD Test type Gene Panel Targeted Variant GTD Location The Hospital for Sick Children GTD Gene/Platform/Region List TPMT (*2, *3A, *3B, *3C), NUDT15 (*3 & *5) GTD Category Hematology GTD Disease/Condition New Leukemia Diagnosis