Single Gene test: TPMT
| Test Information | |
|---|---|
| Test Name | Single Gene test: TPMT |
| Lab (Location) | Sunnybrook Health Sciences Centre |
| Category | Pharmacogenetics |
| Subcategory | Thiopurine S-methyltransferase deficiency (TPMT) |
| Gene/Platform/Region List | TPMT (c.238G>C (p.Ala80Pro)), TPMT (c.460G>A (p.Ala154Thr)), TPMT (c.719A>G (p.Tyr240Cys)) |
| Test type | Targeted Variant |
| Samples Accepted | Blood, DNA |
| Indications Diagnosis | Pharmacogenetics |
| Test Methodology | Real Time PCR |
| Methodology Notes | TaqMan assay; Targeted Mutation |
| Diseases/Conditions | Thiopurine S-methyltransferase deficiency |
| Notes | Drug hypersensitivity Before requesting this test, please contact the lab for information regarding eligibility and availability of testing for your patient |